Brandon Mears first competed in ANW 5, where he completed the qualifying course. In the semi-finals, he failed the Salmon Ladder, not moving on to Vegas.
He returned in ANW 7, where he completed the qualifying course again. In the semi-finals, he failed the Body Prop but still advanced to Vegas. In Vegas, he became the tallest competitor (6'5'') to clear Stage 1 that season. However, in Stage 2, he failed the Unstable Bridge.
In ANW 8, Mears completed the qualifying course for the third time in a row. In the city finals, he shockingly failed the Salmon Ladder, just like in ANW 5, once again not moving on to Vegas. He placed 17th overall.
Mears returned in ANW 9, with major news that his wife, Erika, is pregnant with his first child. It is also worth noting that Mears has formed a group known as the "Windy City Warriors", with Dan Polizzi, Ethan Swanson, and Tyler Yamaguchi, who all live in the same city. Mears dominated the qualifying course with the second-fastest time.
However, he failed to make it to Vegas for the second consecutive year when he fell on the third obstacle, the Broken Pipes, failing the dismount. Even worse, Dan Polizzi and Ethan Swanson both fell there as well, with Tyler Yamauchi being the only "Windy City Warrior" to clear the Broken Pipes and eventually move on to Vegas. He placed 27th overall in the Kansas City finals.
In ANW 10, he returned to compete in Indianapolis. However, he shockingly failed on the Block Run, making it the first time that he didn't complete a qualifying course, let alone fail to make the top 30.
He was later shown supporting the other Windy City Warriors during the city finals. Since the other three made the top 15, he was the only WCW to not advance to Vegas.
In ANW 11, he returned to compete in Cincinnati, with his son Ashton on the sidelines. His qualifying run was digested, but it was shown that he failed the Sling Shot, making it the second consecutive year in which he failed on a qualifying course. This time, however, he still made the top 30 by placing 25th overall.
During the city finals, he officially confirming having another child, Joelle, being born. Running for his family, he got redemption on the balance obstacle and the Salmon Ladder and, for the first time in his career. he completed the course. He placed 4th and advanced to the national finals for the first time since American Ninja Warrior 7. Even better was that Dan Polizzi also finished, so both Towers of Power would compete together for the first time ever.
In Vegas, his run was digested, but it was shown that he failed the Diving Boards.